Endocrine Abstracts

Objective: To evaluate the health-related quality of life (HRQoL) in children and adolescents with constitutional tall stature (CTS).Materials and methods: Sixty-two patients (20 males and 42 females) with CTS aged 9.3–16.4 years (12.9±2.4 years, mean±S.D.) were enrolled in this study. Sixty-eight normal subjects (24 males and 44 females) aged 9.8–16.2 years (13.1±2.1 years) served as controls. The evaluation of th...

Aim: To estimate efficiency of long acting somatostatin analog (Oktreotid-Depot, Ltd ‘FarmSyntez’, Russia) in acromegaly treatment.Material and methods: Twenty-five patients with the confirmed acromegaly diagnosis, active phase, receiving Oktreotid-Depot therapy within 6–12 months in a single dose of 20–40 mg/month. Every three months dynamics of clinical signs, basal IGF-1 and GH levels and pituitary adenoma size were analyzed.<p...

Objective: To evaluate the pituitary hormone axes in adolescents with constitutional tall stature (CTS).Materials and methods: About 120 patients (54 males and 66 females) with CTS aged 9.6–16.5 years (13.6±2.7 years, mean±S.D.) were enrolled in this study. Sixty-eight normal subjects (24 males and 44 females) aged 9.8–16.2 years (13.1±2.1 years), who were comparable in socioeconomic and nutritional terms, served a...

Objective: To report a case of Cushing’s syndrome due to ectopic ACTH secretion and to evaluate role of somatostatin analogues for the localization and postoperative treatment of adrenocorticotropin-secreting bronchial carcinoid tumor.Methods: We describe the clinical presentation of our case and discuss its management.Results: A 57-year-old woman presented with symptoms and physical findings strongly suggestive of Cushing syn...